Aciclovir Cream 5% (Aciclovir)
4.73 / 234

Aciclovir Cream 5% (Aciclovir)

4.73 / 234

Aciclovir cream is a medicine for external use with antiviral properties. The medication is used to fight the outward symptoms of a viral infection, particularly herpes. However, complete recovery requires taking oral antiviral drugs.

The cream rapidly restores the skin, eliminating disease symptoms like blisters, ulcers, and erosions accompanied by burning, itching, and pain. You can use it as a first-aid drug when the first symptoms of herpes appear.

Aciclovir Cream 5%

Drug Info

  • Brand Names: Zovirax Cream, Acivir Cream, Zoster Cream;
  • Active Ingredient: Aciclovir;
  • Manufacturer: Bausch Health Companies Inc, GlaxoSmithKline, Cipla.

Aciclovir cream and its active substance Aciclovir

The drug substance of the cream is an equivalent of the natural DNA component known as guanosine and is highly effective for some types of herpes. When applied to the skin, the cream blocks the replication of the virus in infected cells but doesn't affect DNA synthesis in healthy cells.

The drug works immediately after use, and you can see the visible result of the treatment within 2-3 days. The cream has proven effective in treating herpetic rashes and reducing the severity of pain.

Indications for use

It is an external use drug for viral infections, including:

  • Herpes simplex;
  • Primary or recurrent genital herpes;
  • Lip herpes;
  • Chickenpox;
  • Shingles.

Aciclovir cream is only effective for herpes viruses and won't help relieve symptoms caused by other viruses, such as human papillomavirus.

Also, you can't use the medication to treat fungal infections like thrush. Use the cream as prescribed by a doctor or according to the instructions.

Treatment regimens and dosages

The cream is available in dosages of 5 g and 10 g with the same active substance content. The treatment regimen is as follows:

  • Clean the skin area affected by the virus;
  • Apply a small amount of cream and distribute it evenly;
  • Use it 5 times a day.

A doctor may recommend a different application frequency depending on the severity of the infection. Apply the cream during the day, with a break at night.

The treatment duration is 5 - 10 days. If symptoms of infection persist at the end of treatment, stop using the drug and consult a doctor.

Use Aciclovir cream for genital herpes in the same way. You should separately discuss the dosage and regimen for children under 12 with a doctor.

Recommendations for use

To increase the effectiveness of treatment, follow these rules:

  • Use the drug at regular intervals;
  • Apply the cream in a thin layer to prevent an allergic reaction to the active substance;
  • After application, rub the cream into the skin with massaging movements;
  • Avoid mixing the cream with other drugs and skin care products;
  • Don't take a shower or bath immediately after using the cream.

Don't apply the drug to the mucous membranes of the eyes or mouth to prevent irritation. When applying the cream, use a fingertip or rubber gloves to avoid contact with the infected area of the skin.

If you quickly see the effect, continue treatment to consolidate the result. Don't withdraw the drug on your own.

The effectiveness of treatment largely depends on when it is started. The sooner you start using the drug, the sooner you will see results. Use Aciclovir cream at the first symptoms of herpes or suspicion of it in the form of tingling and other unpleasant sensations.

ATTENTION! An opened tube of the medication is for individual use. Keep the medicine private from other people to avoid transmitting the virus.

Missed Dose

If you forget to apply the cream on time, do it as soon as you remember. If it is near time for the next use, wait for it and apply the cream according to the prescribed regimen.


Aciclovir cream practically doesn't get into the blood, but you should use it with caution if you have these medical conditions:

  • Allergy to Aciclovir or other components of the drug;
  • Immune system diseases (AIDS, HIV);

To avoid possible adverse reactions, inform a doctor about all your diseases before treatment.

ATTENTION! The drug only deals with the external symptoms of a disease. If you use the remedy for genital herpes, remember that you may pass the infection to your partner.

Use of Aciclovir cream during pregnancy

You should discuss using Aciclovir cream during pregnancy with a doctor. Aciclovir has been shown to be safe when administered orally, and there is currently no evidence of possible fetal defects when used in pregnant women.

There is also no data on whether Aciclovir gets into breast milk, as it does with oral use. If you are breastfeeding, consult a doctor on the drug's safety.

Possible side effects

The drug is usually well-tolerated, and side effects are rare, mainly having the form of skin reactions. The most common side effects are as follows:

  • Dry skin;
  • Skin peeling;
  • Skin burning;
  • Skin itching;
  • Swelling;
  • Red skin.

More serious side effects are also possible, such as a severe allergic reaction with the following symptoms:

  • Swelling of the lips or tongue;
  • Labored breathing;
  • Severe rash and itching;
  • Fever.

If side effects are pronounced and don't go away while using Aciclovir cream, or you have serious side effects, consult a doctor.

In some cases, you may have unusual side effects. Please don't ignore them. Any negative health changes should be a reason to consult a doctor.

Aciclovir cream: interaction with other drugs

Don't use the drug with other medicines for external use. At the moment, there is no data on the interaction of the cream with any oral medications. However, to avoid possible adverse reactions, inform a doctor about all the medications you use.

Can you use Aciclovir cream and tablets together? Yes, you can do it in case of a severe infection, but treatment must be under the supervision of a doctor.


Store Aciclovir cream at a temperature below 25°С in a dark place and out of reach of children and animals. Don't store the drug in the fridge. Don't use the drug if the expiration date has passed or the packaging is damaged.

The best offer for Aciclovir cream online on the market

Our pharmacy offers Aciclovir cream at a favorable price compared to other sellers. We guarantee the effectiveness and safety of the drug and its compliance with the appropriate EU standards. We work all over Europe and will deliver your order directly to your home from the nearest warehouse. We also maintain 100% anonymity, delivering all orders in impersonalized, discreet packaging. When ordering from us, you also get these benefits:

  • Aciclovir cream over the counter;
  • Delivery within a few days;
  • 24/7 support;
  • Convenient payment methods (VISA, MasterCard, American Express, or bank transfer).

When buying the drug at our pharmacy, you save time and can start treatment at once. If you need help, contact our experts, who will answer all your questions.

How to buy Aciclovir cream online

For the convenience of our customers, we developed a simple order form. Placing an order takes only a few minutes. To buy Aciclovir cream online, fill out the appropriate fields, including:

  • Drug name;
  • Dosage;
  • Quantity;
  • Delivery address.

We will quickly complete your order and send it to the specified address. If you have difficulties while placing an order, please get in touch with our support team. Our managers are available 24/7 and will provide you with the necessary assistance. Place your order now, and we will deliver it within a few days.

  • Jean Bowens

    Zoster cream works for me. But I must prevent sun and wind exposure for blisters to heal quickly. So, I mostly stay home when the outbreak comes.

  • Coney Blossom

    I'm only partly satisfied by its effects. It does not prevent the formation of cold sores or discomfort. However, it may help to lessen the size of the blisters.

  • Riley Gooden

    When I get a cold sore (tingle), I apply Acivir cream right away, and it prevents blisters. The only problem is that it tastes awful to me.

  • Chad Faison

    The medication is beneficial if you catch the cold sores at the correct time. Anyway, I'm starting oral meds now for quicker results.

  • Clive Epps

    I no longer use Zoster cream. No matter how much I have tried, there has been almost no effect. However, the same drug in the tablets saved me from herpes for a few days.

  • Penny Emmanuel

    I am 23 years old and have recently experienced the first severe outbreak of cold sores. It was horrible, and I was annoyed by the unattractive sores. I went to the doctor, and she prescribed the cream. I saw a positive change in less than 24 hours. So I do believe this is a worthy medicine.

  • Holly Desir

    My first experience with this cream happened on the third day of the outbreak, so bumps were already there. The med is fantastic! It immediately prevented my cold sore from worsening, and began healing it. Now that I have it, I'm hoping it will work even better if I use it immediately at the first symptom.

  • Mildred Macon

    I bought Acivir cream hoping it would help to get rid of herpes quickly, but this stuff did not suit me at all. At the site of application, there was swelling and redness. I had to throw it out.

  • Bobby Fluellen

    Herpes bothers me about 2 times a year when I lack vitamins or have a cold. That's when I take Zoster cream out of my first aid kit. Excellent cream. Always helps just in a few days.

  • India Billups

    Great medicine. You can cure cold sores on your lips in 3 days. I recommend it.

  • Hart Augustin

    I have mixed impressions about this product. I like it, and it somehow helps with herpes, but the big problem is that I often have outbreaks. Maybe I should consider taking the pills.

  • Ann Shavers

    I spent a lot of money and time on Acivir cream. In my case, I have to constantly take pills to keep the herpes from coming back. Unfortunately, I have no alternatives.

  • Ellen Chatman

    The cream helps me better than any tablet. After two or three days of using it, the bumps dry, and my lips look normal.

  • Katie Gatling

    I deal with herpes comprehensively and take pills. I always have cream for emergencies. If there is a bump ( that happens to me very rarely), it takes a maximum of 4 days to treat.

  • Wendy Mccray

    One of the greatest remedies for HSV or cold sores available! When I see a cold sore developing, I immediately apply the cream. The discomfort is instantly relieved, and the ache stops! Worth every cent.

  • Sidney Booker

    It doesn't work on me… Zoster cream appears to accomplish nothing more than keep herpes in its current state, not allowing bumps to grow.

  • Jeremy Etienne

    As soon as I feel dry or there is a hint of some irritation, I apply Acivir cream. I strictly follow the instructions. If you fail to prevent the problem, bump heals in about 5 days. Most importantly - apply the cream with a cotton swab and do not touch the blister. The product helps. Recommend. Good luck with the treatment!

  • Ned Dawkins

    It does not make skin dry. Unlike other similar drugs, it perfectly copes with its purpose.

  • Ethel Bolden

    It is the only cream that helps me prevent bumps. As soon as I feel tingling, I immediately apply it. So I do not have to suffer from pain. The only drawback is the price of the drug. For me, the cream is too expensive.

  • Wednesday Moss

    I was so shy of herpes on my lips that I just locked myself in the house for two weeks when this happened to me (usually about two times a year). I tried a bunch of ointments, but nothing worked. Aciclovir was the last on my list of trials and errors, and I can say with precision and full responsibility that this is the only remedy that removes bumps in a few days. Totally recommend it.

  • Frank Spates

    Aciclovir cream helps perfectly and copes with its task. But I do not understand why it is so expensive.

  • Vance Black

    Herpes on my lips causes me a lot of inconvenience. Besides, it is very ugly and disgusts many people. Unfortunately, these things appear suddenly; personally, I do not have a tingling stage. I am very glad that I found this cream. After applying the product, literally in one night, bumps noticeably decrease in size, and on the second day, they become invisible. This is just a miracle!

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